• 2011-01-20

    2011.1.20-1.31 读书笔记(不断更新) - [reading note]

    版权声明:转载时请以超链接形式标明文章原始出处和作者信息及本声明
    http://robinhawking.blogbus.com/logs/102470465.html

     

    • social cognition

      Behavioural-variant frontotemporal dementia: diagnosis, clinical staging, and management【review】
      Recently, criteria proposed for bvFTD define three levels of diagnostic certainty: possible, probable, and definite. neuropsychological testing designed to detect impairment in decision making, emotion processing, and social cognition.A recently developed staging instrument shows much promise for monitoring patients and evaluating therapies, which at present are aimed at symptom amelioration. 
      http://www.thelancet.com/journals/laneur/article/PIIS1474-4422(10)70299-4/abstract?rss=yes
      额颞叶性痴呆的临床诊疗回顾。这篇等着要全文。

    The Lancet Neurology

     

     

    • Fluoxetine for motor recovery after acute ischaemic stroke (FLAME): a randomised placebo-controlled trial
      In patients with ischaemic stroke and moderate to severe motor deficit, the early prescription of fluoxetine with physiotherapy enhanced motor recovery after 3 months. Modulation of spontaneous brain plasticity by drugs is a promising pathway for treatment of patients with ischaemic stroke and moderate to severe motor deficit.

      早期运用氟西汀可改善缺血性卒中患者的肢体运动功能恢复。 

      The Lancet Neurology



     

    • Renin-angiotensin system blockade and cognitive function in patients at high risk of cardiovascular disease: analysis of data from the ONTARGET and TRANSCEND studies

      In patients with cardiovascular disease or diabetes, different approaches to blocking of the renin-angiotensin system had no clear effects on cognitive outcomes. Although patients with the lowest systolic blood pressure had the greatest preservation of cognitive function, meta-regression analyses did not show any benefits of blood-pressure lowering on cognition over several years of treatment.
      抑制肾素血管紧张素系统,对心血管疾病及糖尿病患者的认知功能未显示明确作用。 

      The Lancet Neurology

     

     

     

     

    • Randomized Controlled Trial of Cognitive Behavioral Therapy vs Standard Treatment to Prevent Recurrent Cardiovascular Events in Patients With Coronary Heart Disease

    A CBT (cognitive behavioral therapy) intervention program decreases the risk of recurrent CVD(cardiovascular disease)  and recurrent acute myocardial infarction. This may have implications for secondary preventive programs in patients with coronary heart disease.
    认知行为治疗可以降低心血管疾病及复发性急性心肌梗死患者的危险系数,起到再发的二级预防作用。
     





    • Albuminuria and Decline in Cognitive Function
       Factors that contribute to albuminuria may contribute to cognitive decline, supporting the notion that both conditions share a common microvascular pathogenesis.
      低蛋白血症与认知功能减退可能有相同的路径。

    Archives of Internal Medicine





    • Transient Ischemic Attack and Acute Ischemic Stroke Associations With Retinal Microvascular Signs
      Patients with TIA and acute stroke may share similar risk factors or pathogenic mechanisms.
      Stroke

      http://stroke.ahajournals.org/cgi/content/short/42/2/404?rss=1








    • A critical role for IGF-II in memory consolidation and enhancement

      IGF-II may represent a novel target for cognitive enhancement therapies.

      现在,用大鼠所做实验表明,施用“胰岛素样生长因子-II” (IGF-II) (一般与身体组织生长和修复有关的蛋白),可以显著增强记忆保持、促进被称为“长时程增强”的记忆指标和防止忘记。IGF-II通过启动能导致“突触增强”的信号级联网络发挥作用,在紧接着学习之后的短时间内最为有效。因此,IGF-II是调控认知增强的一个潜在目标。


      《自然》

      http://www.nature.com/nature/journal/v469/n7331/abs/nature09667.html








    • White Matter Damage and the Effect of Matrix Metalloproteinases in Type 2 Diabetic Mice After Stroke
      Mice with diabetes mellitus have increased brain hemorrhage and show more severely injured WM(white matter) than mice without diabetes mellitus after stroke. MMP-9 upregulated in mice with diabetes mellitus may exacerbate WM damage after stroke in mice with diabetes mellitus.
      Stroke
      http://stroke.ahajournals.org/cgi/content/short/42/2/445?rss=1
















     

     

     


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  • 看来你真的是一个爱学习的人阿....我工作3年了,从未在下班时间看过医学书